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DEPARTMENT OF PHARMACEUTICAL CHEMISTRY

(SYNTHESIS OF NOVEL CHEMICAL ENTITIES)



ABOUT THE DEPARTMENT


The Department of Pharmaceutical Chemistry established in the year 2009, aims to impart quality education in Pharmaceutical Chemistry at UG, PG and doctorate levels. This programme was tailored so that the students receive a sound knowledge in the aspects of Organic Chemistry, Medicinal Chemistry, Biochemistry, Analytical Chemistry and Drug Discovery. The department has the required facilities for full characterization of organic compounds and polymers. Several analytical techniques such as FTIR, GC, HPLC, etc are available. The faculty members and research scholars of this department are highly qualified in designing and synthesizing new chemical entities, their characterization and pharmacological evaluation. The department is successful in getting financial support from various funding agencies like ICMR, New Delhi, BRNS, Mumbai, CSIR, New Delhi RGUHS, Bangalore and VGST Bangalore. The focus of the department is to synthesize new chemical entities for the treatment of cancer, diabetes and tuberculosis using computer aided drug designing with the availability of high speed computers on silicon graphics works station with Sybyl software from Tripos USA. The department also filed patents and working towards commercialisation

FACILITIES IN THE DEPARTMENT


The department is well equipped with sophisticated instruments like HPLC, FT-IR, UV-Visible spectrophotometer, parallel synthesizer, Microwave assisted synthetic system, Microwave assisted extraction system, and in addition, the department has a computational facility for designing drug candidates. Department has the facility for custom synthesis of small heterocyles and new chemical entities (NCEs), Ligand and structure based drug design, in silico virtual screening and other molecular modelling techniques.

LIST OF SOPHISTICATED EQUIPMENTS AVAILABLE IN THE DEPARTMENT


S.No.
Name of the equipment
Make and model
01

Sybyl Drug design software Tripos USA
02 Parallel Synthesizer Aditya Scientific
03 Microwave assisted synthetic system Catalyst
04 Microwave assisted extraction system Catalyst
05 FTIR Bruker
06 HPLC Shimadzu
07 Digital melting point apparatus EIE Instruments
08 U.V spectrophotometer (UV-2450) Shimadzu
09 U.V spectrophotometer Rigol
10 UV chamber EIE Instruments
11 Hot air oven EIE Instruments
12 Gas Chromatograph Mayura Analytical Pvt. Ltd.
13 Magnetic stirrer with hot plates EIE Instruments
14 Heating metals EIE Instruments
15 Rotary flash evaporator (PBU-6) Superfit Rotavap
16 Rotary flash evaporator (HS2005 S/N) Hahn Shin Scientific Co.(south Korea)
17 Nitrogen gas assembly Mahantesh
18 Nephlo-turbidometer Systronics
19 Photofluorometer-152 Systronics


Expert and Experienced Team

Dr. Shrinivas Joshi

Professor and Head

Dr. Channabasappa Hallikeri

Associate Professor

Sri. Shriram Purohit

Assistant Professor

Ms. Sandhya Chinnamulagund

Assistant Professor

Ms. Tabasum Killedar

Assistant Professor

Mrs. Kavita Apte

Assistant Professor

Mrs. Vidya Kamatar

Assistant Professor

Mr. Rajesh Patil

Assistant Professor

Sri. Shivakumar Kotrashetti

Assistant Professor

LAB FACILITIES